Before starting to take sildenafil, you should first consult with your doctor, as it may interfere with certain medications including vitamins, minerals, herbal products, and other prescription products.
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Some of these medications include nitrates, which are frequently prescribed to treat chest pain and angina, as sildenafil may cause a rapid and risky decrease in blood pressure and can lead to fainting, heart attack or stroke. If you have taken sildenafil, then you need to wait at least 24 hours for the drug to leave your system before nitrates can be used.
Another medication that sildenafil interferes with are beta blockers, which are used to treat high blood pressure or prostate difficulties. Your doctor may recommend a lower dose of sildenafil. Protease inhibitors, that are used to treat HIV, may also be affected by sildenafil, so your doctor may limit the dose to a maximum of 25 mg every 48 hours.
Approximately 15 percent of people taking sildenafil experience side effects. These side effects are usually mild and do not last more than a few hours. They include fever, headaches, flushing, muscle aches, nasal infection or stuffiness, vision problems, nosebleeds, sleeplessness, dizziness or light headedness, fainting, shortness of breath, stomach upset, diarrhea, or heartburn. Some cases of sudden hearing loss and tinnitus have also been reported, and this reaction has caused labeling to be revised and list this side effect under Precautions and Adverse Reactions.
Vision problems are also seen in a limited number of patients taking this drug, and include sensitivity to light, blurred vision, impaired blue/green color distinction, and a decrease or loss of sight. The cause of these problems is attributed to a decrease in blood flow to the optic nerve. You should contact your doctor immediately if any of these side effects persist.
During sexual activity, if you experience dizziness or nausea, develop pain or tingling in your chest, arms, neck or jaw, you need to contact your doctor immediately as you may be experiencing serious side effects from sildenafil citrate.
You need to let your doctor know if you have any drug allergies, or any of the following conditions that may affect your tolerance of sildenafil.
- Heart disease or heart rhythm problems
- A recent history of heart attack, stroke, or heart rhythm disorder
- Congestive heart failure
- High or low blood pressure
- Coronary artery disease
- Liver or kidney disease
- A blood cell disorder such as leukemia, multiple myeloma, or sickle cell anemia
- A bleeding disorder such as hemophilia
- A stomach ulcer
- A physical deformity of the penis
- Retinitis pigmentosa
- If you have been advised to avoid sexual intercourse for health reasons
- You are pregnant or planning on becoming pregnant during treatment, or if you are breast feeding a baby
If you think you may have overdosed on Sildenafil citrate, seek emergency medical attention. Symptoms include chest pain, nausea, irregular heartbeat, feeling lightheaded, or fainting.
Allergic reactions to sildenafil include skin rashes, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience these reactions, you should immediately seek emergency medical help.