Sildenafil Citrate: How does it work?

How Sildenafil Citrate works

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Sildenafil Citrate


Sildenafil (Viagra) is the most popular erectile dysfunction medication in the world.

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In simple terms, Sildenafil Citrate works by increasing the amount of blood that flows to the penis. This causes a healthy erection, something the users of the drug want.

Most men, up to a certain age at least, take their ability to achieve a healthy erection for granted. They do not consider that impotence may be a problem for them, and when it does happen, it can be a distressing experience, and can even cause families to fall apart. The problem can cause depression in men. The idea that sexual potency is limited and may even be gone forever from a man’s life is one that many men do not even want to contemplate. The emotional impact of erectile dysfunction can be devastating, with many sufferers reporting feelings linked to depression. Some sufferers fear intimacy in their relationships. Others suffer from high anxiety.

The problem is quite common. In fact, over 50% of men between the age of 40 and 70 reported recently that they have had at least one incidence of erectile dysfunction. This problem gets even worse as men get older, with one in three 70 year olds reporting the problem.

Men who smoke are more likely to suffer from erectile dysfunction, as are men who are overweight. Those who suffer from any kind of hypertension or heart disease are even more likely to suffer from impotence, since such conditions restrict the flow of blood to organs.

When a man is sexually excited, Sildenafil works to create an erection by increasing blood flow. As the sexual experience finishes, the erection dies away.

The erection process takes place when nitric oxide is released to the penile corpus cavernosum. This process then activates an enzyme known as guanylate cyclase. All of this leads to some relaxation of the smooth muscles in this area of the penis, which results in erection.

Sildenafil Citrate does not work without sexual stimulation. It was a common belief that the drug was so powerful that it was able to create erections without the penis being stimulated. However, this is not the case. Unless the penis is directly stimulated when the drug has been taken, there will be no erection. This is because a group of chemicals need to be released into the penis for an erection to take place. Sildenafil has no direct control over the creation of these chemicals. All it does is control how long the chemicals stay in the penis. This feature of the drug allows the self-conscious male to feel at ease with the whole process.
As regards how quickly the drug works, the answers are reasonably clear. Users should not expect an immediate erection. The whole process has to be carefully planned when it comes to the build-up towards the sex act. The truth is that many variables do have a part to play. In the end the speed at which the drug works is down to the makeup of the individual who takes it.

There have been reports of the drug taking effect in as little as 14 minutes. More commonly, the drug takes effect in around half an hour. This is why it has to be taken carefully, and with a degree of planning. For the majority of users, the effects of the drug can last for up to four hours. When it comes to the common experience, however, the drug can decrease in effect at around the two hour stage.

There are a number of factors that do affect the length of the drug’s effect. Those over 65 years old will probably find that the drug does not last as long. Those with kidney disease or complications can find that the drug does not have as powerful an effect as they might wish.

Linked to the existence of the enzymes in the whole process is the fact that eating a high fat meal may significantly reduce the effect of the drug. In addition, if you take the drug along with certain other medications, the effects can be severely limited. It is worth consulting with your physician for information regarding this.