Contraindications of using Sildenafil Citrate
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Sildenafil Citrate
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The use of sildenafil or Viagra is used to treat erectile dysfunction in men experiencing impotence the drug has helped many men, but not without risk.
What does contraindication mean?
Contraindication is a condition or factor that increases the risk involved in using a particular drug, carrying out a medical procedure, or engaging in a certain activity. An example of this is would be, never give a baby aspirin because of the risk of Reye’s syndrome.
Why use Sildenafil (Viagra)?
Sildenafil is used for a variety of reasons but most common is ED. Sildenafil will help constricted tubes relax and allow more blood to enter the penis quicker. This makes the penis become elongated and rigid making an erection. Other medical conditions this drug is used for include pulmonary hypertension, altitude sickness and use in sports.
PDE-5 inhibitors
Phoshodiesterase type 5 inhibitor, or PDE-5 inhibitor, is a drug used to block the derivative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. This drug is used in the treatment of ED. All PDE-5 inhibitors are contraindicated in people who use sildenafil.
Cardiovascular System
If you have been advised against sexual intercourse due to cardiovascular risks by your doctor, then you should not take sildenafil. Since sildenafil citrate was released, doctors have been cautioned not to prescribe this drug to men with severe cardiovascular disease and especially to those men using nitrates such as nitroglycerin to treat heart failure.
Since sildenafil citrate helps achieve and sustain an erection by targeting nerves acting in the smooth muscle increasing blood flow, it also seems to increase sympathetic nerve activity (the nerve that causes the blood vessels to constrict.) There have been many reports of heart attack, heart arrhythmia and even deaths that have been related to people who were using Viagra.
Hepatic impairment
Hepatic impairment is decreased liver function also know as chronic liver disease. This is when the liver destructs over a period of time. Some studies show that a lower dosage of sildenafil citrate can be used, about 25mg and the patient is fine. Always check with a doctor before starting any type of drug.
Hypotension
Hypotension or abnormally low blood pressure is often associated with shock though it’s not the only cause. Hypotension is when there is a reduce in blood volume called hypovolemia. This can happen from hemorrhaging, insufficient fluid intake or excessive fluid loss from diarrhea or vomiting. Sildenafil lowers the blood pressure and you don’t have to be a doctor to know if you already have low blood pressure and then you take something that also lowers it, it will create problems. People with hypotension are advised against using sildenafil.
Recent stroke or heart attack
People who have had a recent stroke or heart attack are advised against taking sildenafil because it lowers blood pressure and interacts with nitrates. Drugs that are commonly used in patients with heart problems contain nitrates. Patents taking nitrates for heart disease and sildenafil are prone to develop hypotension and experience fainting. Patients taking nitrates for coronary artery disease should never take sildenafil.
There are contraindications for taking for taking any type of drug and that includes sildenafil. Patients that want to take sildenafil are advised to talk to a doctor to see and report any and all medical problems.